Pharmaceutical Powder 99% Purity Procaine Hydrochloride CAS 51-05-8

Pharmaceutical Powder 99% Purity Procaine Hydrochloride CAS 51-05-8

Procaine Hydrochloride Details:

Product Name	Procaine hydrochloride
Synonym	aminocaine;anadolor;anesthesol;anestil; atoxicocaine
CAS No	51-05-8
MF	C13H21ClN2O2
MW	272.77
EINECS	200-077-2
Molecular Structure
Chemical Properties	white crystalline powder
Assay	99%
Usage	Procaine is a local anesthetic of the amino ester group that is primarily used as a topical anesthetic. Procaine is also used to control the pain of intramuscular injection of penicillin as well as in dentistry.
Packaging Details	25kg/drum or as required

Procaine Hydrochloride COA:

Procaine Hydrochloride Application:

Procaine Hydrochloride is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses.

In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation.

Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine led to the increase of dopamine and serotonin levels in the brain.Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest.

Procaine can also cause allergic reactions causing the individuals to have problems with breathing,

rashes, and swelling. Allergic reactions to procaine are usually not in response to procaine itself,

but to its metabolite PABA. About one in 3000 people have an atypical form of pseudocholinesterase,

which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.

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