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Pharmaceutical Intermediate Promethazine Hydrochloride CAS 58-33-3

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Pharmaceutical Intermediate Promethazine Hydrochloride CAS 58-33-3

China Pharmaceutical Intermediate Promethazine Hydrochloride CAS 58-33-3 supplier
Pharmaceutical Intermediate Promethazine Hydrochloride CAS 58-33-3 supplier Pharmaceutical Intermediate Promethazine Hydrochloride CAS 58-33-3 supplier

Large Image :  Pharmaceutical Intermediate Promethazine Hydrochloride CAS 58-33-3

Product Details:

Place of Origin: China
Brand Name: JNJG
Certification: ISO 9001, USP, BP

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: usd(1-10)
Packaging Details: Discreet packing ways as your requirement, 100% go through
Delivery Time: within 24 hours after your payment
Payment Terms: Western Union, MoneyGram, T/T, Bank Transfer, Bitcoin
Supply Ability: 1000kg/month
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Detailed Product Description
CAS: 58-33-3 MF: C17H21ClN2S
MW: 320.88 EINECS: 200-375-2
Appearance: White Solid Usage: Antihistaminic, Antiemetic, CNS Depressant

Pharmaceutical Intermediate Promethazine Hydrochloride CAS 58-33-3

 

 

Quick Detail:

Product Name

 

Promethazine hydrochloride

 

Synonym

 

Phenothiazine hydrochloride;Promethazine Hcl

 

CAS NO

 

58-33-3

 

MF

 

C17H21ClN2S

 

MW

 

320.88

 

EINECS

 

200-375-2

 

Purity

 

99%

 

Appearance

 

White Powder

 

Melting Point

 

230-232°C

 

Grade

 

Pharma Grade

 

Usage

 

For the treatment of allergic disorders,and nausea/vomiting.

 

 

 

Description:

 

Promethazine is a neuroleptic medication and first-generation antihistamine of the phenothiazine family. The drug has strong sedative and weak antipsychotic effects.It also reduces motion sickness and has antiemetic and anticholinergic properties(via its action on the dopamine receptor D2). In some countries it is prescribed for insomnia when benzodiazepines are contraindicated. It is available in many countries under many brand names. Promethazine was developed in the mid 1940s when a team of scientists from Rhône-Poulenc laboratories were able to synthesize it from phenothiazine and a diamine side chain of diphenhydramine

Promethazine hydrochloride occurs as a white to faint yellow, practically odorless, crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. It is soluble in water and freely soluble in alcohol.

 

 

Specification:

Item Specification

 

Result

 

Description White crystalline powder

 

White crystalline powder

 

Identification IR,UV conform

 

Conform

 

Loss on drying ≤0.5ml

 

0.21ml

 

Residue on ignition Not more than 0.2%

 

0.06ml

 

Iron Not more than 0.005%

 

0.0018%

 

Heavy metals Not more than 0.001%

 

0.0006%

 

Related substances Total: Not more than 1.0%
Individual: Not more than 0.5%

 

0.32%
0.14%

 

E-isomer Not more than 0.3%

 

0.19%

 

 

Organic volatile impurities

 

Conforms Conforms
Assay 99.0~101.0%

 

99.51%

 

Conclusion

 

Conform with USP30

 

 

 

Application:

 

Promethazine is used to prevent and treat nausea and vomiting related to certain conditions(such as before/after surgery, motion sickness). It is also used to treat allergy symptoms such as rash, itching, and runny nose. It may be used to help you feel sleepy/relaxed before and after surgery or to help certain narcotic pain relievers (such as meperidine) work better. It may also be used for a short time to treat a runny nose due to the common cold.

Promethazine is an antihistamine and works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. Its other effects (such as anti-nausea, calming, pain relief) may work by affecting other natural substances (such as acetylcholine) and by acting directly on certain parts of the brain.

 

 

Use:

 

(1)Antihistaminic, antiemetic,CNS depressant.
(2)Stool softener.
(3)With aminophylline in the treatment of asthma.
(4)For the treatment of allergic disorders, and nausea/vomiting.
(5)Dubbed hibernation and injection for artificial hibernation.

 

Pharmaceutical Intermediate Promethazine Hydrochloride CAS 58-33-3

 

 

Advantage:

 

1,High quality with competitive price
(1)Standard: Enterprise Standard
(2)All Purity≥99%
(3)We are manufacturer and can provide factory price.

 

2,Fast and safe delivery
(1)Parcel can be sent out in 24 hours after payment. Tracking number available
(2)Secure and discreet shipment.Various transportation method for your choice.
(3)Customs pass rate ≥99%

 

3,We have clients throughout the world.
(1)Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
(2)Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.

 

Contact Details
Jinan  Jia  Ge  Biological  Technology  Co., Ltd.

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